Thermal injury to the skin manifest as coagulation necrosis with microvascular thrombosis in areas that most of the damage. Surrounding tissue usually had burns that are not too severe, with stasis and hiperemia that its boundaries are not clear. Areas that potentially could be saved, earned perfusion of microcirculation damage. If patients with extensive burns do not immediately get the proper fluid resuscitation, the shock can occur due to burns and wounds will be part of the injured but still alive, and will continue to be necrosis. Quinine, prostanoid, histamine, and oxygen radicals appear to play an important role in determining the severity of tissue injury. Ibuprofen can save the skin blood vessels and reduce edema arising early after burns.
Fluid resuscitation is to strengthen the formation of edema in the tissue, both suffered burns or not. Edema is not will always be bad, if recovered will not leave permanent damage. The liquid that comes out and the room is very similar intravascular plasma, both in terms of protein content and the electrolyte. Baxter and Shire have shown that loss of sodium is approximately 0.5 to 0.6 meq / kg body weight /% body surface burned. Acute hemolysis caused by direct damage to red blood cells due to heat.Activation of complement due to burns and subsequent production of oxygen radicals by neutrophils increased osmotic fragility of red blood cells, and cause hemolysis lasted for several days after thermal injury. In the first 24 hours after injury, hematocrit values as high as 70% relatively often found in a previously healthy young people.
The increase in capillary permeability caused a decrease in intravascular volume and cardiac output. Although systemic arterial pressure in the first place can often be maintained near normal values, but the ongoing downsizing of intravascular volume may lead to hypotension, decreased peripheral perfusion, and tissue acidosis. Loss of intravascular fluid to the extent of the burns that exceed 20 to 25% of the surface of the body too quickly to be resolved by the partial correction of fluid deficit through intracellular fluid shifts. At first, the increase in capillary permeability would result in a net loss of plasma volume obligate. Within 24 hours of a second after the burn, capillary permeability returned to normal, with a small increase in the net and intravascular plasma volume.
Replacement fluid is burned off and the network is a cornerstone in the treatment and prevention is shock due to burns. With appropriate crystalloid fluid resuscitation for 12 to 24 hours, cardiac output will increase to levels above normal, reflecting the early symptoms of a post hipermetabolisme burns. Data such as these emphasize the importance of measuring cardiac output over the determination of blood volume as an indication of the success of resuscitation. Although at first the patient may experience hypotension and hypovolemia, but blood pressure often times will remain among the low-to low-normal with adequate systemic perfusion after resuscitation began.Experimental research has shown that the kidney is the organ with a perfusion of the worst after a burn. With resuscitation, the renal blood flow will return to normal only after perfusion of other visceral organs recover. Thus, an adequate renal perfusion can be interpreted as an adequate blood flow also to other organs. Urine comes out is an indication of the most precise and easy to monitor resuscitation.
Fluid resuscitation is to strengthen the formation of edema in the tissue, both suffered burns or not. Edema is not will always be bad, if recovered will not leave permanent damage. The liquid that comes out and the room is very similar intravascular plasma, both in terms of protein content and the electrolyte. Baxter and Shire have shown that loss of sodium is approximately 0.5 to 0.6 meq / kg body weight /% body surface burned. Acute hemolysis caused by direct damage to red blood cells due to heat.Activation of complement due to burns and subsequent production of oxygen radicals by neutrophils increased osmotic fragility of red blood cells, and cause hemolysis lasted for several days after thermal injury. In the first 24 hours after injury, hematocrit values as high as 70% relatively often found in a previously healthy young people.
The increase in capillary permeability caused a decrease in intravascular volume and cardiac output. Although systemic arterial pressure in the first place can often be maintained near normal values, but the ongoing downsizing of intravascular volume may lead to hypotension, decreased peripheral perfusion, and tissue acidosis. Loss of intravascular fluid to the extent of the burns that exceed 20 to 25% of the surface of the body too quickly to be resolved by the partial correction of fluid deficit through intracellular fluid shifts. At first, the increase in capillary permeability would result in a net loss of plasma volume obligate. Within 24 hours of a second after the burn, capillary permeability returned to normal, with a small increase in the net and intravascular plasma volume.
Replacement fluid is burned off and the network is a cornerstone in the treatment and prevention is shock due to burns. With appropriate crystalloid fluid resuscitation for 12 to 24 hours, cardiac output will increase to levels above normal, reflecting the early symptoms of a post hipermetabolisme burns. Data such as these emphasize the importance of measuring cardiac output over the determination of blood volume as an indication of the success of resuscitation. Although at first the patient may experience hypotension and hypovolemia, but blood pressure often times will remain among the low-to low-normal with adequate systemic perfusion after resuscitation began.Experimental research has shown that the kidney is the organ with a perfusion of the worst after a burn. With resuscitation, the renal blood flow will return to normal only after perfusion of other visceral organs recover. Thus, an adequate renal perfusion can be interpreted as an adequate blood flow also to other organs. Urine comes out is an indication of the most precise and easy to monitor resuscitation.
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